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Salicylanilide pyrazinoates inhibit in vitro multidrug-resistant Mycobacterium tuberculosis strains, atypical mycobacteria and isocitrate lyase.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20140312
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A new approach for pyrazinamide susceptibility testing in Mycobacterium tuberculosis.
Microbial drug resistance (Larchmont, N.Y.) 20120801
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Ubiquitin-proteasome system inhibitors and AMPK regulation in hepatic cold ischaemia and reperfusion injury: possible mechanisms.
Clinical science (London, England : 1979) 20120701
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In vitro antibacterial and antifungal activity of salicylanilide pyrazine-2-carboxylates.
Medicinal chemistry (Shariqah (United Arab Emirates)) 20120701
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Role of metal ions on the activity of Mycobacterium tuberculosis pyrazinamidase.
The American journal of tropical medicine and hygiene 20120701
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Poly[μ(2)-aqua-μ(2)-(pyrazine-2-carboxyl-ato)-lithium].
Acta crystallographica. Section E, Structure reports online 20120701
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The chemotherapy of tuberculosis: past, present and future.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20120601
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catena-Poly[[[diaqua-nickel(II)]-μ-pyrazine-2-carboxyl-ato-silver(I)-μ-pyrazine-2-carboxyl-ato] nitrate dihydrate].
Acta crystallographica. Section E, Structure reports online 20120501
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Disorder in the anionic part of catena-poly[[(pyrazine-2-carboxyl-ato)copper(II)]-μ-pyrazine-2-carboxyl-ato].
Acta crystallographica. Section E, Structure reports online 20120401
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Investigation of in situ oxalate formation from 2,3-pyrazinedicarboxylate under hydrothermal conditions using nuclear magnetic resonance spectroscopy.
Inorganic chemistry 20120319
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Structural motifs in phenylbismuth heterocyclic carboxylates--secondary interactions leading to oligomers.
Dalton transactions (Cambridge, England : 2003) 20120121
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Pyrazinoic acid efflux rate in Mycobacterium tuberculosis is a better proxy of pyrazinamide resistance.
Tuberculosis (Edinburgh, Scotland) 20120101
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Electrochemical and spectroscopic investigations of isoniazide and its analogs with ds.DNA at physiological pH: evaluation of biological activities.
European journal of medicinal chemistry 20120101
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Patterns of pncA mutations in drug-resistant Mycobacterium tuberculosis isolated from patients in South Korea.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20120101
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Two-drug antimicrobial chemotherapy: a mathematical model and experiments with Mycobacterium marinum.
PLoS pathogens 20120101
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Synthesis and characterization of organic impurities in bortezomib anhydride produced by a convergent technology.
Scientia pharmaceutica 20120101
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MSMEG_2731, an uncharacterized nucleic acid binding protein from Mycobacterium smegmatis, physically interacts with RPS1.
PloS one 20120101
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Nanoparticle delivery of anti-tuberculosis chemotherapy as a potential mediator against drug-resistant tuberculosis.
The Yale journal of biology and medicine 20111201
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catena-Poly[[(6-carb-oxy-pyrazine-2-carboxyl-ato)lithium]-μ-aqua].
Acta crystallographica. Section E, Structure reports online 20111201
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Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosis.
Science (New York, N.Y.) 20110916
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Microbiology. Pyrazinamide--old TB drug finds new target.
Science (New York, N.Y.) 20110916
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Cytotoxic and antimicrobial activities of Cu(II), Co(II), Pt(II) and Zn(II) Complexes with N,O-chelating heterocyclic carboxylates.
Archiv der Pharmazie 20110901
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Tris(3-amino-pyrazine-2-carboxyl-ato-κN,O)diaqua-erbium(III) tetra-hydrate.
Acta crystallographica. Section E, Structure reports online 20110901
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Poly[[(μ-3-amino-pyrazine-2-carboxyl-ato-κN,O:O')diaqua-(μ-oxalato-κO,O:O,O)lanthanum(III)] monohydrate].
Acta crystallographica. Section E, Structure reports online 20110901
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8-Hy-droxy-2-methyl-quinolinium tetra-chlorido(pyrazine-2-carboxyl-ato-κN,O)stannate(IV) methanol monosolvate.
Acta crystallographica. Section E, Structure reports online 20110901
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catena-Poly[[[bis-(3-amino-pyrazine-2-carboxyl-ato)triaqua-praseodymium(III)]-μ-3-amino-pyrazine-2-carboxyl-ato-[(3-amino-pyrazine-2-carboxyl-ato)diaqua-formatopraseodymium(III)]-μ-3-amino-pyrazine-2-carboxyl-ato] hexa-hydrate].
Acta crystallographica. Section E, Structure reports online 20110901
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Pyrazinamide, but not pyrazinoic acid, is a competitive inhibitor of NADPH binding to Mycobacterium tuberculosis fatty acid synthase I.
Bioorganic & medicinal chemistry letters 20110815
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catena-Poly[[(aqualithium)-μ-3-carboxypyrazine-2-carboxylato-κO,N:O,N] monohydrate].
Acta crystallographica. Section E, Structure reports online 20110801
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Poly[[diaquadi-μ(2)-cyanido-bis-(μ(2)-pyrazine-2-carboxyl-ato)dicopper(I)copper(II)] dihydrate].
Acta crystallographica. Section E, Structure reports online 20110701
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Identification and functional characterization of uric acid transporter Urat1 (Slc22a12) in rats.
Biochimica et biophysica acta 20110601
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Triethyl-ammonium tetra-chlorido(pyrazine-2-carboxyl-ato-κN,O)stannate(IV).
Acta crystallographica. Section E, Structure reports online 20110601
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New three-dimensional metal-organic framework with heterometallic [Fe-Ag] building units: synthesis, crystal structure, and functional studies.
Inorganic chemistry 20110404
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3-Meth-oxy-carbonyl-1-methyl-pyrazinium tetra-chlorido(pyrazine-2-carboxyl-ato-κN,O)stannate(IV).
Acta crystallographica. Section E, Structure reports online 20110201
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Poly[[hepta-μ(2)-aqua-bis-(μ(2)-pyrazine-2-carboxyl-ato)dibarium] bis-(pyrazine-2-carboxyl-ate)].
Acta crystallographica. Section E, Structure reports online 20110201
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Effects of low incubation temperatures on the bactericidal activity of anti-tuberculosis drugs.
The Journal of antimicrobial chemotherapy 20110101
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Antimicrobial Susceptibility Testing of Mycobacterium bovis Isolates from Michigan White-Tailed Deer during the 2009 Hunting Season.
Veterinary medicine international 20110101
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Crystal structure of the pyrazinamidase of Mycobacterium tuberculosis: insights into natural and acquired resistance to pyrazinamide.
PloS one 20110101
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Poly[di-μ-aqua-μ(4)-(pyrazine-2,5-dicarboxyl-ato)-dilithium(I)].
Acta crystallographica. Section E, Structure reports online 20110101
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Structure-Activity relationship in mutated pyrazinamidases from Mycobacterium tuberculosis.
Bioinformation 20110101
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Characteristics of pncA mutations in multidrug-resistant tuberculosis in Taiwan.
BMC infectious diseases 20110101
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Antimycobacterial evaluation of pyrazinoic acid reversible derivatives.
Current pharmaceutical design 20110101
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Rapid colorimetric testing for pyrazinamide susceptibility of M. tuberculosis by a PCR-based in-vitro synthesized pyrazinamidase method.
PloS one 20110101
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Yersinia enterocolitica and Yersinia pseudotuberculosis Detection in Foods.
Journal of pathogens 20110101
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Synthesis, structure and magnetic properties of two new azido-Co(II) coordination architectures: from ferromagnetic coupling to single-chain-magnets.
Dalton transactions (Cambridge, England : 2003) 20101214
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Kinetics and inhibition of nicotinamidase from Mycobacterium tuberculosis.
Biochemistry 20101109
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Reductive degradation of pyrazine-2-carboxylate by a newly isolated Stenotrophomonas sp. HCU1.
Biodegradation 20100901
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Monoclinic modification of aquadi-n-butyl-bis-(pyrazine-2-carboxyl-ato-κN,O)tin(IV).
Acta crystallographica. Section E, Structure reports online 20100901
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A series of transition metal-azido extended complexes with various anionic and neutral co-ligands: synthesis, structure and their distinct magnetic behavior.
Dalton transactions (Cambridge, England : 2003) 20100828
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Synthesis and anti-mycobacterial evaluation of some pyrazine-2-carboxylic acid hydrazide derivatives.
European journal of medicinal chemistry 20100801
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catena-Poly[[[tetra-aqua-erbium(III)]-μ-oxalato-κO,O:O,O] [bromidobis(pyrazine-2-carboxyl-ato-κN,O)cuprate(II)] tetra-hydrate].
Acta crystallographica. Section E, Structure reports online 20100801
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Xanthine oxidase inhibition by allopurinol increases in vitro pyrazinamide-induced hepatotoxicity in HepG2 cells.
Drug and chemical toxicology 20100701
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The near future: improving the activity of rifamycins and pyrazinamide.
Tuberculosis (Edinburgh, Scotland) 20100501
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Poly[aqua-(μ-pyrazine-2-carboxyl-ato-κN,O:O)(μ-pyrazine-2-carboxyl-ato-κN,O:O')lead(II)].
Acta crystallographica. Section E, Structure reports online 20100501
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Photoluminescent lanthanide-organic bilayer networks with 2,3-pyrazinedicarboxylate and oxalate.
Inorganic chemistry 20100405
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Peruvian and globally reported amino acid substitutions on the Mycobacterium tuberculosis pyrazinamidase suggest a conserved pattern of mutations associated to pyrazinamide resistance.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20100301
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N'-[1-(4-Amino-phen-yl)ethyl]pyrazine-2-carbohydrazide.
Acta crystallographica. Section E, Structure reports online 20100301
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QSAR modeling of a set of pyrazinoate esters as antituberculosis prodrugs.
Archiv der Pharmazie 20100201
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Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7) in human.
Biological & pharmaceutical bulletin 20100101
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Molecular epidemiological study of pyrazinamide-resistance in clinical isolates of mycobacterium tuberculosis from South India.
International journal of molecular sciences 20100101
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Surveillance of pyrazinamide susceptibility among multidrug-resistant Mycobacterium tuberculosis isolates from Siriraj Hospital, Thailand.
BMC microbiology 20100101
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Epidemiology of gout.
Arthritis research & therapy 20100101
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Poly[hexa-aqua-bis(μ(3)-terephthalato)(μ(2)-terephthalato)diytterbium(III)].
Acta crystallographica. Section E, Structure reports online 20100101
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Poly[bis-(μ(2)-pyrazine-2-carboxyl-ato)-κN,O:O';κN,O:O-cadmium(II)].
Acta crystallographica. Section E, Structure reports online 20100101
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Ligand-based modification of the structures and optical properties of new silver(I)-rhenate(VII) oxide/organic hybrid solids.
Inorganic chemistry 20091207
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A polymorph of diaqua-bis(pyrazine-2-carboxyl-ato-κN,O)copper(II).
Acta crystallographica. Section E, Structure reports online 20091201
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Tetra-ethyl-ammonium tricarbonyl-chlorido-(pyrazine-2-carboxyl-ato-N,O)rhenate(I).
Acta crystallographica. Section E, Structure reports online 20091101
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Substituted N-Phenylpyrazine-2-carboxamides: synthesis and antimycobacterial evaluation.
Molecules (Basel, Switzerland) 20091020
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Combined Mössbauer spectral and density functional theory determination of the magnetic easy-axis in two high-spin iron(II) 2-pyrazinecarboxylate complexes.
Inorganic chemistry 20090907
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Poly[diaqua-(μ(2)-oxalato-κO,O:O,O)(μ(2)-pyrazine-2-carboxyl-ato-κN,O:O,O')neodymium(III)].
Acta crystallographica. Section E, Structure reports online 20090901
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Interpreting expression data with metabolic flux models: predicting Mycobacterium tuberculosis mycolic acid production.
PLoS computational biology 20090801
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Poly[[hemi-μ(4)-oxalato-hemi-μ(2)-oxalato-bis-(μ(3)-pyrazine-2-carboxyl-ato)erbium(III)silver(I)] monohydrate].
Acta crystallographica. Section E, Structure reports online 20090801
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Derivatives of pyrazinecarboxylic acid: 1H, 13C and 15N NMR spectroscopic investigations.
Magnetic resonance in chemistry : MRC 20090701
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Poly[[hemi-μ(4)-oxalato-hemi-μ(2)-oxalato-bis-(μ(3)-pyrazine-2-carboxyl-ato)neodymium(III)silver(I)] monohydrate].
Acta crystallographica. Section E, Structure reports online 20090701
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Lipophilic pyrazinoic acid amide and ester prodrugs stability, activation and activity against M. tuberculosis.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628
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Poly[di-μ(2)-azido-μ(3)-pyrazine-2-carboxyl-ato-cadmium(II)].
Acta crystallographica. Section E, Structure reports online 20090501
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Protective effects of coffee-derived compounds on lipopolysaccharide/D-galactosamine induced acute liver injury in rats.
The Journal of pharmacy and pharmacology 20090401
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The identification of orally bioavailable thrombopoietin agonists.
Bioorganic & medicinal chemistry letters 20090301
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3-(3-Amino-phenyl-sulfon-yl)aniline.
Acta crystallographica. Section E, Structure reports online 20090201
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Genome-wide analysis of the PreA/PreB (QseB/QseC) regulon of Salmonella enterica serovar Typhimurium.
BMC microbiology 20090101
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Mutations found in the pncA gene of Mycobacterium tuberculosis in clinical pyrazinamide-resistant isolates from a local region of China.
The Journal of international medical research 20090101
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What lies behind serum urate concentration? Insights from genetic and genomic studies.
Genome medicine 20090101
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Poly[diaqua-μ-oxalato-μ-pyrazine-2-carbox-yl-ato-lanthanum(III)].
Acta crystallographica. Section E, Structure reports online 20090101
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Metal and mixed-metal coordination polymers synthesized with pyrazine-2-carboxylate.
Dalton transactions (Cambridge, England : 2003) 20081121
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Vibrational spectroscopic studies and ab initio calculations of a substituted amide of pyrazine-2-carboxylic acid--C12H10ClN3O.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081115
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Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans.
The Journal of biological chemistry 20081003
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Poly[diaqua(μ(2)-oxalato-κO,O:O,O)(μ(2)-pyrazine-2-carboxyl-ato-κN,O:O')cerium(III)].
Acta crystallographica. Section E, Structure reports online 20081001
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Synthesis and structures of a new series of silver-vanadate hybrid solids and their optical and photocatalytic properties.
Inorganic chemistry 20080915
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4-Carboxy-pyridazin-1-ium chloride.
Acta crystallographica. Section E, Structure reports online 20080801
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Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13).
The Journal of biological chemistry 20080613
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Synthesis and antimycobacterial evaluation of substituted pyrazinecarboxamides.
European journal of medicinal chemistry 20080501
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Mechanistic implications of the active species involved in the oxidation of hydrocarbons by iron complexes of pyrazine-2-carboxylic acid.
Dalton transactions (Cambridge, England : 2003) 20080421
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Diaqua-bis(pyrazine-2-carboxyl-ato-κN,O)manganese(II) dihydrate.
Acta crystallographica. Section E, Structure reports online 20080401
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Characterization of Mycobacterium tuberculosis nicotinamidase/pyrazinamidase.
The FEBS journal 20080201
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Interpretation of the multiple vanadium-oxygen bonds in the central VO(eta2-O2)+ group. Synthesis, structure, supramolecular interactions and DFT studies for complexes with 2,2'-bipyridine, 1,10-phenanthroline, pyrazinato(1-) and pyrazinamide ligands.
Dalton transactions (Cambridge, England : 2003) 20080107
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Suppression of blood lipid concentrations by volatile Maillard reaction products.
Nutrition (Burbank, Los Angeles County, Calif.) 20080101
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Silymarin protects liver against toxic effects of anti-tuberculosis drugs in experimental animals.
Nutrition & metabolism 20080101
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Medical management of genitourinary tuberculosis.
Indian journal of urology : IJU : journal of the Urological Society of India 20080101
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Dibromidobis(pyrazine-2-carboxylic acid-κN)mercury(II) dihydrate.
Acta crystallographica. Section E, Structure reports online 20080101
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2'-(3-Hydroxy-benzyl-idene)pyrazine-2-carbohydrazide monohydrate.
Acta crystallographica. Section E, Structure reports online 20080101
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Structural determination of hypnosin, a spore germination inhibitor of phytopathogenic Streptomyces sp. causing root tumor in melon (Cucumis sp.).
Journal of agricultural and food chemistry 20071226
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Substituted N-phenylpyrazine-2-carboxamides, their synthesis and evaluation as herbicides and abiotic elicitors.
Molecules (Basel, Switzerland) 20071220
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Effect of silibinin on the pharmacokinetics of pyrazinamide and pyrazinoic acid in rats.
Drug metabolism and disposition: the biological fate of chemicals 20070901
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Agonist lead identification for the high affinity niacin receptor GPR109a.
Bioorganic & medicinal chemistry letters 20070901
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Oxidation of 2-propanol and cyclohexane by the reagent 'hydrogen peroxide-vanadate anion-pyrazine-2-carboxylic acid': kinetics and mechanism.
The journal of physical chemistry. A 20070816
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Discovery of pyrazine carboxamide CB1 antagonists: the introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series.
Bioorganic & medicinal chemistry letters 20070715
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Inhibition of isolated Mycobacterium tuberculosis fatty acid synthase I by pyrazinamide analogs.
Antimicrobial agents and chemotherapy 20070701
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Pyrazinoic acid and its n-propyl ester inhibit fatty acid synthase type I in replicating tubercle bacilli.
Antimicrobial agents and chemotherapy 20070201
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Human renal organic anion transporter 4 operates as an asymmetric urate transporter.
Journal of the American Society of Nephrology : JASN 20070201
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Magnetic properties and molecular structures of binuclear (2-pyrazinecarboxylate)-bridged complexes containing Re(IV) and M(II) (M = Co, Ni).
Dalton transactions (Cambridge, England : 2003) 20070121
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Concentration-dependent mode of interaction of angiotensin II receptor blockers with uric acid transporter.
The Journal of pharmacology and experimental therapeutics 20070101
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[Ln2(C2O4)2(pyzc)2(H2O)2]n[Ln = Pr (1), Er (2)]: novel two-dimensional lanthanide coordination polymers with 2-pyrazinecarboxylate and oxalate.
Inorganic chemistry 20061225
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Effects of weak acids, UV and proton motive force inhibitors on pyrazinamide activity against Mycobacterium tuberculosis in vitro.
The Journal of antimicrobial chemotherapy 20061101
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pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates from the southeast region of Brazil.
The Journal of antimicrobial chemotherapy 20061101
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Polar symmetry and intercalation of new multilayered hybrid molybdates: [M2(pzc)2(H2O)x][Mo5O16] (M = Co, Ni).
Inorganic chemistry 20060612
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Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
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Renal urate transport.
Rheumatic diseases clinics of North America 20060501
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Versatility in the binding of 2-pyrazinecarboxylate with iron. Synthesis, structure and magnetic properties of iron(II) and iron(III) complexes.
Dalton transactions (Cambridge, England : 2003) 20060407
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Substituted pyrazinecarboxamides: synthesis and biological evaluation.
Molecules (Basel, Switzerland) 20060329
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Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome.
Structure (London, England : 1993) 20060301
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The paradox of pyrazinamide: an update on the molecular mechanisms of pyrazinamide resistance in Mycobacteria.
The Journal of communicable diseases 20060301
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Acid-base characterization of 5-hydroxypyrazine-2-carboxylic acid and the role of ionic equilibria in the optimization of some process conditions for its biocatalytic production.
Analytical and bioanalytical chemistry 20051001
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A density functional theory study of the mechanism of free radical generation in the system vanadate/PCA/H2O2.
The journal of physical chemistry. B 20050929
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Structural origin of chirality and properties of a remarkable helically pillared solid.
Inorganic chemistry 20050919
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Phenolsulfonphthalein transport by potential-sensitive urate transport system.
European journal of pharmacology 20050822
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Hydrothermal syntheses and structures of two mixed-valence copper(I,II) 2-pyrazinecarboxylate coordination polymers.
Inorganic chemistry 20050530
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Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family.
The Biochemical journal 20050515
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Synthesis and characterization of ReO4-containing microporous and open framework structures.
Inorganic chemistry 20040906
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Anaerobic incubation conditions enhance pyrazinamide activity against Mycobacterium tuberculosis.
Journal of medical microbiology 20040801
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Self-assembly of diorganotin(IV) moieties and 2-pyrazinecarboxylic acid: syntheses, characterizations and crystal structures of monomeric, polymeric or trinuclear macrocyclic compounds.
Dalton transactions (Cambridge, England : 2003) 20040621
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Iron enhances the antituberculous activity of pyrazinamide.
The Journal of antimicrobial chemotherapy 20040201
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Function and localization of urate transporter 1 in mouse kidney.
Journal of the American Society of Nephrology : JASN 20040201
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A mixed matrix of 3-hydroxypicolinic acid and pyrazinecarboxylic acid for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of oligodeoxynucleotides.
Rapid communications in mass spectrometry : RCM 20040101
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Mode of action of pyrazinamide: disruption of Mycobacterium tuberculosis membrane transport and energetics by pyrazinoic acid.
The Journal of antimicrobial chemotherapy 20031101
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Urate transport via human PAH transporter hOAT1 and its gene structure.
Kidney international 20030101
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The curious characteristics of pyrazinamide: a review.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20030101
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Augmentation of H2 photoproduction in Rhodopseudomonas palustris by N-heterocyclic aromatic compounds.
Biotechnology letters 20030101
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Synthesis and antimycobacterial activity of pyrazine and quinoxaline derivatives.
Journal of medicinal chemistry 20021205
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Functional analysis and molecular model of the human urate transporter/channel, hUAT.
American journal of physiology. Renal physiology 20020701
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Investigation of the effects of concomitant caffeine administration on the metabolic disposition of pyrazinamide in rats.
Biopharmaceutics & drug disposition 20020701
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Growth-promoting activity of pyrazinoic acid, a putative active compound of antituberculosis drug pyrazinamide, in niacin-deficient rats through the inhibition of ACMSD activity.
Bioscience, biotechnology, and biochemistry 20020701
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Escherichia coli genes involved in resistance to pyrazinoic acid, the active component of the tuberculosis drug pyrazinamide.
FEMS microbiology letters 20020604
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Effects of pyrazinamide on fatty acid synthesis by whole mycobacterial cells and purified fatty acid synthase I.
Journal of bacteriology 20020401
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Recurrence of carboxylic acid-pyridine supramolecular synthon in the crystal structures of some pyrazinecarboxylic acids.
The Journal of organic chemistry 20020125
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Conditions that may affect the results of susceptibility testing of Mycobacterium tuberculosis to pyrazinamide.
Journal of medical microbiology 20020101
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A new packing variant of catena-poly[[aquachlorocopper(II)]-mu-pyrazine-2-carboxylato-O,N:N'].
Acta crystallographica. Section C, Crystal structure communications 20011201
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Crystal structure and mechanism of catalysis of a pyrazinamidase from Pyrococcus horikoshii.
Biochemistry 20011127
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Anion-directed crystallization of coordination polymers: syntheses and characterization of Cu(4)(2-pzc)(4)(H(2)O)(8)(Mo(8)O(26)).2H(2)O and Cu(3)(2-pzc)(4)(H(2)O)(2)(V(10)O(28)H(4)).6.5H(2)O (2-pzc = 2-pyrazinecarboxylate).
Inorganic chemistry 20010312
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Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action.
Bioorganic & medicinal chemistry letters 20010122
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pncA mutations in clinical Mycobacterium tuberculosis isolates from Korea.
BMC infectious diseases 20010101
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The molecular basis of resistance to isoniazid, rifampin, and pyrazinamide in Mycobacterium tuberculosis.
Respiratory research 20010101
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Correlation of pncA sequence with pyrazinamide resistance level in BACTEC for 21 mycobacterium tuberculosis clinical isolates.
Microbial drug resistance (Larchmont, N.Y.) 20000101
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Quantitative structure-activity relationships for the in vitro antimycobacterial activity of pyrazinoic acid esters.
Journal of medicinal chemistry 19960816
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Pyrazinoic acid esters with broad spectrum in vitro antimycobacterial activity.
Journal of medicinal chemistry 19950929
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Activity of n-propyl pyrazinoate against pyrazinamide-resistant Mycobacterium tuberculosis: investigations into mechanism of action of and mechanism of resistance to pyrazinamide.
Antimicrobial agents and chemotherapy 19950601
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Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii.
Biochemical pharmacology 19940817
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Antimycobacterial activity of a series of pyrazinoic acid esters.
Journal of medicinal chemistry 19920403
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Pyrazinamide and pyrazinoic acid activity against tubercle bacilli in cultured human macrophages and in the BACTEC system.
The Journal of infectious diseases 19900701
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Does pyrazinoic acid as an active moiety of pyrazinamide have specific activity against Mycobacterium tuberculosis?
Antimicrobial agents and chemotherapy 19890801
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Role of rifampicin in arthralgia induced by pyrazinamide.
Tubercle 19830601
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Pyrazinamide susceptibility and amidase activity of tubercle bacilli.
The American review of respiratory disease 19670301