99754-06-0 | 4-Chloro-2-(3-(4-pentylphenyl)acrylamido)benzoic acid

Packsize	Purity	Availability	Price	Discounted Price
25mg	98%	in stock	$168.00	$117.00
100mg	98%	in stock	$313.00	$219.00

Description

• Catalog Number: AW54724
• Chemical Name: 4-Chloro-2-(3-(4-pentylphenyl)acrylamido)benzoic acid
• CAS Number: 99754-06-0
• Molecular Formula: C21H22ClNO3
• Molecular Weight: 371.8573
• MDL Number: MFCD00210755
• SMILES: CCCCCc1ccc(cc1)/C=C/C(=O)Nc1cc(Cl)ccc1C(=O)O

Computed Properties

• Complexity: 486
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 8
• XLogP3: 6.3

Literature

• Role of phospholipase A(2) in retrograde transport of ricin.

  Toxins 20110901

• A role for phospholipase A2 activity in membrane tubule formation and TGN trafficking.

  Traffic (Copenhagen, Denmark) 20101201

• Assembly of an intact Golgi complex requires phospholipase A2 (PLA2) activity, membrane tubules, and dynein-mediated microtubule transport.

  Biochemical and biophysical research communications 20091120

• Cytoplasmic phospholipase A2 antagonists inhibit multiple endocytic membrane trafficking pathways.

  Biochemical and biophysical research communications 20091030

• The distinct stage-specific effects of 2-(p-amylcinnamoyl)amino-4-chlorobenzoic acid on the activation of MAP kinase and Cdc2 kinase in Xenopus oocyte maturation.

  Cellular signalling 20050401

• Simultaneous activation of PLA2 and PLC are required to promote acrosomal reaction stimulated by progesterone via G-proteins.

  Molecular reproduction and development 20050101

• Regulation of the water channel aquaporin-1: isolation and reconstitution of the regulatory complex.

  Cell biology international 20040101

• Lipoxygenase products regulate nitric oxide and inducible nitric oxide synthase production in interleukin-1beta stimulated vascular smooth muscle cells.

  Hypertension research : official journal of the Japanese Society of Hypertension 20030201

• Human platelets respond differentially to lysophosphatidic acids having a highly unsaturated fatty acyl group and alkyl ether-linked lysophosphatidic acids.

  The Biochemical journal 20020801

• Origin of Ca2+ necessary for carbachol-induced contraction in longitudinal muscle of the proximal colon of rats.

  Japanese journal of pharmacology 20011201

• Calcium-independent phospholipase A(2) is required for human monocyte chemotaxis to monocyte chemoattractant protein 1.

  Journal of immunology (Baltimore, Md. : 1950) 20010915

• Vasopressin-stimulated Ca2+ spiking in vascular smooth muscle cells involves phospholipase D.

  American journal of physiology. Heart and circulatory physiology 20010601

• Arachidonyltrifluoromethy ketone, a phospholipase A(2) antagonist, induces dispersal of both Golgi stack- and trans Golgi network-resident proteins throughout the cytoplasm.

  Biochemical and biophysical research communications 20010223

• Simvastatin and Ca(2+) signaling in endothelial cells: involvement of rho protein.

  Biochemical and biophysical research communications 20010119